Families	Sub-groups	Typical size-range a	DR b	Ends c	IRs d	Nb ORF	Frameshift	Chemistry e	Comments	Mechanism
IS1	-	740-1180	8-9	GGnnnTG	Y	2	ORFAB	DDE		copy-and-paste co-integrate
	1 ORF	800-1200	0-9			1
	ISMhu11	900-4600	0-10		Y	2	ORFAB
IS1595	ISPna2	1000-1150	8	GGCnnTG	Y	1		DDNK		copy-and-paste ?
	+pass	1500-2600	8
	ISH4	1000	8	CGCTCTT		1		DDNK
	IS1016	700-745	7-9	GGGgctg		1		DDEK
	IS1595	900-1100	8	CcTGATT		1		DDNK + ER4R7
	ISSod11	1000-1100	8	nnnGcnTATC		1		DDHK + ER4R7
	ISNwi1	1080-1200	8	ggnnatTAT		1		DDEK + ER4
	+pass	1750-4750	8			1
	ISNha5	3450-7900	8	CGGnnTT		1		DDER/K
IS3	IS150	1200-1600	3-4	TG	Y	2	ORFAB	DDE	ORFB coordinates defined between two STOP codons since there are no inherent initiation signals and the orf is not translated alone.	copy-paste
	IS407	1100-1400	4	TG
	IS51	1000-1400	3-4	TG
	IS3	1150-1750	3-4	TGa/g
	IS2	1300-1400	5	TG
IS481	-	950-1300	4-15	TGT	Y	1				copy-paste ?
IS4	IS10	1200-1350	9	CT	Y	1		DDE	Hairpin intermediate	cut-and paste
	IS50	1350-1550	8-9	C					Hairpin intermediate
	ISPepr1	1500-1600	7-8	-T-AA
	IS4	1400-1600	10-13	-AAT
	IS4Sa	1150-1750	8-10	CA
	ISH8	1400-1800	10	CAT
	IS231	1450-5400	10-12	CAT		1 or + *			* Passenger genes
IS701	-	1400-1550	4		Y	1		DDE
ISH3	-	1225-1500	4-5	C-GT	Y	1		DDE
IS1634	-	1500-2000	5-6	C	Y	1		DDE
IS5	IS903	950-1150	9	GG	Y	1		DDE
	ISL2	850-1200	2-3			1
	ISH1	900-1150	8	-GC		1
	IS5	1000-1500	4	Ga/g		1
	IS1031	850-1050	3	GAa/g		1
	IS427	800-1000	2-4	Ga/g		2	ORFAB
IS1182		1330-1950	0-60		Y	1		DDE
IS6	-	700-900	8	GG	Y	1		DDE		co-integrate
IS21	-	1750-2600	4-8	TG	Y	2 *		DDE	* istB : helper of transposition
IS30	-	1000-1700	2-3		Y	1		DDE		copy and paste
IS66	-	2000-3000	8-9	GTAA	Y	3 *		DDE *	* TnpC has the DDE domain
	ISBst12	1350-1900	8-9	GTAA	Y	1		DDE
IS91	-	1500-2000	0		N	1		Y2	Target site GAAC ( ) CAAG	rolling circle
IS110	-	1200-1550	0		N	1		DEDD
	IS1111				Y *				* IRs not at the termini of the IS
IS200/IS605 f	IS200	600-750	0		N	1 *		Y1	* TnpA	peel and paste
	-	1300-2000				2 *		Y1 **	* TnpA + TnpB ;  ** Y1 on TnpA
	IS1341	1200-1500				1 *			* TnpB
IS607	-	1700-2500	0		N	2 *		Serine **	* TnpA + TnpB ;  **  on TnpA
IS256	-	1200-1500	8-9	Ga/g	Y	1		DDE		copy-paste
IS630	-	1000-1400	2 *		Y	1 or 2	ORFAB	DDE	* Target site : often NTAN with duplication of the TA	cut-and paste
IS982	-	1000	3-9	AC	Y	1		DDE
IS1380	-	1550-2000	4-5	CC	Y	1		DDE
ISAs1	-	1200-1500	8-10	CAGGG	Y	1
ISL3	-	1300-2300	8	GG	Y	1
Tn3	-	>3000	0	GGGG	Y	>1		DDE		co-integrate
ISAzo13	-	1250-2200	0-4	Ga/g	Y	1

^a Size range in base pairs (bp) represents the typical range of each group.

^b Direct target repeats in base pairs; ND, not determined; less frequently observed lengths are included in brackets.

^c Conserved terminal based pairs. Capital letters(and capital letters within parentheses) refer to mostly (and often) conserved bases. Lowercase letters separated by slashes indicate alternative conservation at that position.

^d Presence (Y) or absence (N) of terminal inverted repeats.

^e DDE represents the common acidic triad presumed to be part of the active site of the transposase.

^f In the IS200/IS605 family, when the accessory gene TnpB is present, it give the sens of the IS.